Release the Driver: Close all other applications that might be using audio (Chrome, Spotify, Discord) before opening your DAW.

0xc0000001 = STATUS_UNSUCCESSFUL – means USB host controller is resetting the device.

The primary culprits behind this digital silence usually fall into three categories: Driver Conflicts

: Realtek onboard audio drivers or other third-party audio software can clash with Focusrite's ASIO drivers. Connectivity Issues